I've 'sort of' tried Nucynta. I have a new PCP and before my TKR explained to him I was so worried because I can't tolerate any narcotics. They make me dreadfully sick. He wrote me a Rx for Nycynta because it's new and one I hadn't tried. I filled it, and then chose a day where if I got sick it wouldn't be the end of the world. Took one.
Nothing happened as far as making me sick. But, of course, I didn't take it to take away post op pain, either. So, I don't know how effective it is. I just tucked it away as an option to try after my TKR.
It was so expensive - several hundred dollars to fill it, but my PCP had a coupon that picked up whatever my insurance didn't. In the next week Medicare kicked in and they honor NO coupons of any kind, so the only pills I'll ever have are the ones in that first Rx.
I never needed to try them again, as I tried Dilaudid first with this TKR and along with anti-nausea meds, I could tolerate it.
How's the Nucynta working for you?