Working from home is radically different than going out the door each morning. I think you'll be able to handle it without a problem, especially with reduced hours. I worked from home for two years before I retired and loved it. Husband has been working from home for many years, in a similar field to yours. He travels 2-3x a year, but other than that, he's right here.
All this travel and work talk is almost making me wish I had a great job to return to.....almost, but not quite, lol. I am truly grateful that I was able to retire at 62. Color me lazy, though I did clock 40 years of nose to the grindstone.