Diane's Knee Quest finally the real deal

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My main concern is developing a tolerance to them where they won't help my pain. I have been using ibu, either the 800mg rx ones, or the pm otc ones for years and don't have any gastric issues.
It's most unlikely that anyone will get a tolerance to NSAIDs insofar as pain relief is concerned but evidence is that gastric problems/bleeds can occur quite suddenly whether you take them for years or just a day or two. And gastric bleeds in this situation can be quite catastrophic requiring emergency surgery and a transfusion of blood in significant quantities. Much better not to run the risk.
I've never found Tylenol to have any effect on my pain. Any thought? I've (also) heard that too much tylenol can cause liver problems
My experience is, when asked specifically, that Americans say but have tended to take just one regular Tylenol which is 325mg which is why they don't feel any benefit. Because the correct and effective dose is 1,000mg up to 4 times per 24hrs. And yes, Tylenol certainly can have a deleterious effect upon the liver but the key is in the "too much". Provided you don't exceed the recommended amount per 24hrs. which is 4,000mg it is perfectly safe provided also that your liver is healthy!
 
Ok I may give it a new try. With more frequency I have never taken just 1 pill, usually 2 . Two tylenol extra strength are 1000 mg. Will that work well with my tramadol?
 
Yes. It should help you. I used it only post op so I can't tell you that it works for arthritis pain though.
 
So @Josephine I am going to try your tylenol/tramadol regimen for my arthritic painful knee to see if I can get some relief without ibuprofen. Would you think this same routine, maybe minus the 4am one would help me?

This is the routine I am referring to. Thank you.

[Bonesmart.org] Diane's Knee Quest finally the real deal
 
You can but try but I've often said here that the person who comes up with a pain med that adequately manages arthritic pain will very likely get a Nobel Prize for Medicine!
 
Diane, my OS told me to take the Tylenol Arthritis 650mg, is extended release, I had already been using it prior to the surgery, that's the only Tylenol that gives me ant type of relief!
 
You still have to be careful to not take more than 4,000 mg per day. After surgery some pain meds are a narcotic with Tylenol in it. You have to make sure you count that amount in too.
 
Ya @newlybionic after surgery I'll be taking Percocet (oxy 325/10) so I wont be taking the tylenol alone as it's in the oxy's. I have a pretty high tolerance for them. I took them for close to 8 months with my hip nightmare. Once I did not need them I had no problem giving them up. Im not really an addictive type, unless we are talking chocolare or ice cream. :-) I'm looking for something for now to substitute for the ibuprofen I take with tramadol.
 
Yes that's hard to come up with anything that will help because most OS want you to quite anti-inflammatory meds do to there tendency to make you bleed. I hope that you can find something to keep you comfortable until your surgery.
 
Yes, I had to give up the ibu a week before my brain surgery in march. I tried the regular strength tylenol a few days, but was not consistent with it. This time gonna try to see it taking it steadily with the tramadol helps. I know the ibu/tramadol combo does take the edge off. But I dont take that every day for reasons mentioned earlier. No easy answers, are there. Bottom line, old stinks ;-)
 
Diane old doesn't stink it just gets a little challenging,haha, how boring would life be without challenges? Just think we are fixing ourselves up so that we can enjoy our next stage of our lives pain free :wave:
 
Diane old doesn't stink it just gets a little challenging....,haha


Ummm hmm I think I'd have to disagree just a tad :) . I was great till I was 62, then it seemed all downhill from there,,medically speaking.. 7 major surgeries in 5 years. Not my idea of "challenge" , more like "old stinks" but hey, trying to be open minded and see if this one eventually gives me some quality of life back.
 
Yeah, but 65 isn't old!
I'l be 75 soon and that isn't old, either.

My own doctor says "Getting old is great. It's just the side effects that suck."
 
Ha! @Celle good way to put it. Guess I've just had too many side effects these last few years. It's ironic, that when you are young and working your tush off accumulating money for your old age, older people, like even my own parents , tell you, concentrate more on your health, than money. Of course who listens? Haha. Well then you get to that point, and you retire, and all that money you worked so hard to earn & save, does you not one bit of good, to give you back your squandered good health. Then we tell the next generation coming up, and they dont listen either. The cycle continues...
 
Hopefully you have turned the 'medical' corner and you'll bed doing much better after your TKR. I went through a series of surgeries in my 30s and I thought I would never get my health back. Try to stay positive.
 
a series of surgeries in my 30s

Wow, in your 30s? I cant even imagine. My thirties I was in the best shape and health of my life. my husband and I were able to party all night, come home, shower, and go to work. Once I had our son at 36 the partying stopped, but I was so accustomed to little sleep, being up all night with a baby barely phased me. Somedays I think I am paying the price for some of that in my 60.s, karma, or who knows.
 
I'm not sure if that place is still open. They have built so many large hotels here. I live by a few of the ski resorts and also a few miles from the NASCAR racetrack. It's really beautiful here year round but you've got to like snow.
 
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