While I was told it could take 10 for full effect, I was told I should have some benefit before then (i.e., it wasn't like a magic switch would suddenly turn on the pain relief). I agree with
@SarahBee that I would go ahead and call if your appointment isn't real soon. Even if it is next week, the doctor having that information before the appt could let the doc think about next steps before you get there. Is there a portal for communication? I've had good results with those (if the doctor monitors it) because you can leave more information and questions (and maybe get an answer back before your appt) than if you call and talk to a receptionist or asst.