If you have an increase in pain at three weeks, you need to look at what has changed. You mention your medications have. That's okay. If what you are taking now isn't helping, then go back to what worked! You are very early in your recovery and you might very well need the 'big guns' for relief, still.
But what else has changed? Are you icing as much as you were. Elevating as much and correctly? Are you 'up' more? Starting to put together a simple meal or two or tackling laundry? What about your PT now. Could that be to blame?
Look at this from every angle. My Week Three was a hard one, but I finally figured it was mostly emotional. I was more than ready to feel better, darn it!
EVERYTHING and anything will affect your pain levels.