Even if the Celebrex works, it won't work forever...and maybe not even for very long. I've taken diclofenac for years. Worked great at first. I take duloxetine for a bit of anxiety...also helps with pain. I, like you...have tested negative for RA, but my rheumatologist started me on Plaquenil anyway. Didn't notice much difference, but I still take it. All the while, the arthritis kept getting worse, and now I am to a point where the meds aren't helping.
I am also 46. A mom of two. This year...I missed an important field trip with my daughter to the Art Institute of Chicago...because there is no way I could have walked it. Can't go to Costco or the mall anymore. My life is shrinking, and I don't want it to keep getting smaller, know what I mean?
Possible bad outcomes scare me to death...but knowledge is power, so I am learning all I can to minimize my risks.
Think long and hard...very tough decision. I feel better this spring and summer...but I know the pain will become debilitating again as winter comes.
Good luck! At least go ahead with the appt to discuss!