Josephine, I tested highly allergic to Nickel in the blood test that I had done. So I do have an allergy to nickel, quite a predominant one. I also tested positive for being slightly allergic to vanadium and zirconium. I have had nothing but problems since I had my THR in November. I am having a hard time finding a lot of information about nickel allergies and short term and long term affects on my health. I have been hospitalized with tremendous swelling and I had a lot of fluid in my actual hip joint, but they did find any infection in the hip itself. I do antibiotics and the swelling goes down, but it always comes back. I have tremendous pain constantly. Yet, I now have a doctor that still wants to do another hip aspiration and some cortisone shots before he does revision surgery, why????Nickel is one of a triad of metals, iron, nickel and cobalt, so yes, very much it is related but it matters not if you have never had skin reactions.