I have a question to the administrator, moderators or bonesmarties. What are your thoughts or is there any information in the archive library pertaining to smoking before or after surgery with infection in early TKR or TKR revision. I understand that smoking is linked to worse outcome in joint replacement but I'm trying to wrap my head around how smoking can cause you to develop a staph infection and the early stages of a TKR. Thanks in advance. Right TKR revision March 26, 2019. (Depuy Attune Revision Cementless) Right staph infection (Cement antibiotic spacer with 2 rods 6 weeks of antibiotic via PICC line) December 18, 2018. Right TKR April 2012.