Ugh. We did that drive one time, from Killeen to Sacramento. And will NEVER do it again. (And we flew there and then drove our daughter's car here while she was deployed; we didn't have to do a round trip in the car) It took more than a day just to get out of Texas. I think we broke the trip up into 3 or 4 days, which you won't be doing. But, if you can, I suggest giving yourself a couple of days each way, at least, and have the ability to elevate as often as possible. I'd also bring the ice machine along if you have one, and use it whenever you can. If you stay at hotels, as we did, you can fill it from their ice makers, or bring plenty of zip top bags to fill with ice if you don't have, or bring, an ice machine. You can also buy ice along the way to use in the car. Plan to stop and stretch, plus walk around often, also. Just sitting for long stretches is hard on new knees. Overall, don't do more than you have to, and make sure to ice and elevate as often as you can. Bring along OTC pain relief, and maybe a few stronger ones if you find yourself in a lot of pain and need more than Tylenol. Good luck and have some fun!