My new knees are 2 weeks old today. I am rationing my Hydrocod/Apap 5-325 to only take at night, but regular Tylenol 500 mg is alittle like taking nothing at all. I see my surgeon tomorrow and do not know if I will get a new prescription or not. I do not really know how long patients usually stay on the hydrocod, but it seems to help the discomfort level more than Tylenol. This website and forum is great, I have referred to it often and learned much. Thank you.